Principal Investigator

Jie Zhou, MD, MS, MBA, FASA


Dr. Zhou is a staff anesthesiologist at the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital. His main focuses of clinical practice are in Obstetric Anesthesia, Neuro Anesthesia and Acute Pain Medicine. Dr. Zhou graduated from Suzhou Medical College. He completed his clinical Neurosurgery residency and fellowship in China and Japan. He was a post-doctoral fellow in Department of Neurological Surgery, University of Virginia. Dr. Zhou completed a Medical Informatics Fellowship at the School of Medicine, University of California Davis. He graduated with an MBA with focus in Healthcare Management and Information Technology from the School of Management, University of California Davis. He completed an Anesthesia residency and fellowship in Obstetric Anesthesia at the Brigham and Women’s Hospital.

The research undertaken in the Zhou laboratory focuses around the clinical aspects of Obstetric anesthesia, Neuro anesthesia and the Obstetrics related Neurological and Neurosurgical conditions. The laboratory also tests cutting-edge high-tech material, equipment and innovational approaches to improve anesthesia quality and care to patients. One the goals of the laboratory is to identify novel pathways to find solutions for patients with complicated neurological and neurosurgical conditions to go through peripartum or perioperative periods. 

Research Fellows

Minxian Liang, MD​

Minxian graduated from Zhongshan School of Medicine, Sun Yat-sen University in 2016.
Her current research interests focus on clinical studies:
1. Identifying the best sitting position for neuraxial anesthesia by using ultrasound
2. Relationship between wet tap and various risk factors




Jie Luo, MD, PhD

Jie graduated from Chongqing Medical University, China in 2011, and finished her anesthesia residency training at the First Affiliated Hospital of Chongqing Medical University. Her current research interests include:
1. Assess volume status and requirements of parturients
2. Analgesia for parturients with opioids dependence
3. Anesthesia for intra-arterial treatment of acute ischemic stroke


Kyle Jespersen, MD 

Kyle did his medical school and anesthesiology residency at Jefferson University Hospital in Philadelphia, Pennsylvania.  He moved to Boston to be with his wife and to complete a clinical fellowship in obstetrical anesthesia at Brigham and Women’s Hospital.  His research focus is how well anatomic landmarks can help guide residents in placing epidural catheters for labor and delivery in morbidly obese patients.





Tianyue Mi, MS

Tianyue graduated from School of Psychological and Cognitive Sciences, Peking University in 2016. Her current research interests focus on:

1. Risk factors of postpartum depression
2. The relationship between cognitive bias and pain intensity





Britlyn Orgill, MD

Britlyn is an anesthesiology resident at Brigham and Women’s Hospital. She has research interests in medical education and quality improvement. She has previously done research in wound healing, tissue engineering, prostate cancer and competency based medical education.  She also has a background in medical illustration and medical simulation videos. Most recently, as a member of the Center for Anesthesia Innovation and Quality, she has investigated the usage of sugammadex and its drug interactions and presented her work nationally.




Emily Siu, MD

Emily is currently a CA-3 Anesthesiology resident at Brigham and Women’s Hospital. She was born and raised in New York. She graduated summa cum laude from New York University and obtained her medical degree from New York University School of Medicine. Her research interests include clinical studies of physiologic changes associated with regional anesthesia and patient satisfaction with multimodal analgesia regimens.






Ni Tang, MD, PhD 

Ni is from the Affiliated Hospital of Southwest Medical University, Sichuan, China. Her current research interest focus on:
1. Gabapentin and delirium
2. Obstetrician forceps and obstetrician induction





Chunling Wang, MD, PhD

Chunling comes from Shandong University of China as a visiting scholar. She is interested in sleep apnea,especially pregnancy combined with obstructive sleep apnea. Her current research interests focus on the relationship between pregnancy and obstructive sleep apnea. The purpose of her project is to assess obstructive sleep apnea (OSA) and pregnancy complications. The aims include assessing pregnancy complications with diagnosed and undiagnosed OSA, especially parturients with gestational hypertension, gestational diabetes, pre-eclampsia and other adverse outcomes.


Research Assistants

Shuang Fan

Shuang is currently attending Berklee College of Music and Northeastern University. She currently majors in Neuroscience, Electronic Production and Design, Business, and minors in Conducting. She also works as a lab assistant at MIT Brain and Cognitive Sciences. She hopes to pursue a PhD in Neuroscience and get a M.D. and M.B.A degree. Her goal is to promote innovation and improve human life. Her current research interest is to understand and standardize EEG patterns.





Jingui (Annabella) He, RDN, LDN

Annabella graduated from the University of Wisconsin-Madison with a degree in Nutritional Science-Dietetics. After completing a one-year advanced nutrition practice at the Massachusetts General Hospital Dietetic Internship, she became a registered dietitian nutritionist and a licensed dietitian in Massachusetts. Her goal is to study the nutrition interventions for diseases and to inform dietary policies. Her current research interest is to understand the role of nutrients in postpartum depression, pain management and inflammation.





Past Research Fellows

Hui Li, MD

Hui graduated from the Second Military Medical University, China in 2003 and finished his anesthesia residency training at Nanjing Air Force Hospital, China. He is currently working in the Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, China. His research interests include:
1. Secondary uterotonic agents usage during cesarean delivery
2. Relationship of epidural anesthesia and labor progress





Ping Li, MD, PhD

Ping was a visiting scholar from Chongqing Medical University, China. His research interests include:
1. Systemic or Manual Cause for change of Electronic Obstetric Anesthesia Documentation Review of Epic Implementation at the Brigham and Women’s Hospital
2. Effect of long term use of low dose aspirin during pregnancy on postpartum depression
3. Comparison of characteristics of patients undergoing carotid endarterectomy by vascular surgeon and neurosurgeon
4. Efficacy of the qCON monitor in measuring response to nociceptive stimulation during surgery in patients with or without opioid tolerance: a pilot study
​5. Anesthesia management of patients with pheochromocytoma



Mian Peng, MD, PhD

Mian was a Research Fellow at Brigham and Women’s Hospital from 02/2016 to 05/2016. She is currently working as an Associate Professor at the Zhongnan Hospital Wuhan University, China.
Her current research interests include postoperative cognitive dysfunction and postoperative delirium.




Qinjun Chu, MD 

Qinjun was a Research Fellow at Brigham and Women’s Hospital from 10/2015 to 01/2016. He is currently working at the 1st Affiliated Hospital of Zhengzhou University, China.
His research focus is postoperative cognitive dysfunction.






Lin Wang, MD

Lin was a Research Fellow at Brigham and Women’s Hospital from 12/2015 to 06/2016. She is currently working at the Beijing Obstetrics and Gynecology Hospital, China.
Her research focus is Obstetric Anesthesia and labor analgesia of high-risk pregnancy.




Xiaonan Liu, MD, MS

Xiaonan was a Visiting Scholar at Brigham and Women’s Hospital from 05/2015 to 05/2016.
​He is currently working as a visiting consultant at the Queen Elizabeth Hospital, Barbados.
His clinical practice focuses on obstetric anesthesia, neural surgery anesthesia, orthopedic anesthesia, and chronic pain management.